연체동물에서 분리한 신규 스테로이드 화합물

Title
연체동물에서 분리한 신규 스테로이드 화합물
Alternative Title
New Steroids from an Unidentified Ascidian
Author(s)
신희재; 이희승; 노정래
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2004-09-06
Abstract
Sulfated steroids have attracted a great attention by their unusual chemical structures,1 activity against HIV,2-7 and as inhibitors of enzymes8, 9 and have been described from a wide variety of marine organisms, particularly sponges and echinoderms. As part of our continuing search for biologically active natural products from marine organisms, it was found that crude extract of an unidentified marine ascidian exhibited potent cytotoxic activity. Bioassay-guided fractionation of the extract yielded new sulfated streoids and their structures were determined on the basis of spectroscopic data. These compounds exhibited cytotoxicity against human leukemia cell line (K-562).
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/31774
Bibliographic Citation
11th International Symposium on Marine Natural Products, pp.103, 2004
Publisher
Chemical Society of Italy
Type
Conference
Language
English
Publisher
Chemical Society of Italy
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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