Comparison of vitellogenin responses protein and gene expression of to 4-Nonylphenol in Rockfish (Sebastes schlegeli )
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정지현 | - |
dc.contributor.author | R.F.Addsion | - |
dc.contributor.author | 심원준 | - |
dc.contributor.author | 오재룡 | - |
dc.contributor.author | 한창희 | - |
dc.date.accessioned | 2020-07-17T06:52:14Z | - |
dc.date.available | 2020-07-17T06:52:14Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2006-05-11 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/31102 | - |
dc.description.abstract | To investigate the in vivo estrogenic activity of 4-Nonylphenol (4-NP) on reproductive function, we have measured the expression level of rockfish vitellogenin (rVTG) mRNA, concentration of plasma VTG and levels of plasma estradiol-17b (E2) and testosterone (T) by radioimmunoassay (RIA). The level of rVTG mRNA expression was increased at 48 h after injection with 4-NP of 10 mg/kg b.w. and after injection in both male and female rockfish. The level of rVTG mRNA expression was increased at 24 h after injection in male rockfish injected with 4-NP of 25 mg/kg b.w., whereas the level of rVTG mRNA expression was increased at 12 h after injection in female injected with same dosage. Concentrations of plasma rVTG in female and male injected with 4 -NP of 10 mg/kg b.w. and 25 mg/kg b.w. were increased at 72 h after injection. Plasma concentrations of T and E2 in female and male injected with 4-NP were not significantly different between two dosages of 10 mg/kg b.w. and 25 mg/kg b.w. These results suggest that 4-NP may disrupt the reproductive system of immature rockfish by acting directly on vitellogenesis. Immature females injected with 4-NP were more sensitive than immature males. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | SETAC Europe | - |
dc.relation.isPartOf | setac | - |
dc.title | Comparison of vitellogenin responses protein and gene expression of to 4-Nonylphenol in Rockfish (Sebastes schlegeli ) | - |
dc.type | Conference | - |
dc.citation.endPage | 212 | - |
dc.citation.startPage | 212 | - |
dc.citation.title | setac | - |
dc.contributor.alternativeName | 정지현 | - |
dc.contributor.alternativeName | 심원준 | - |
dc.contributor.alternativeName | 오재룡 | - |
dc.identifier.bibliographicCitation | setac, pp.212 | - |
dc.description.journalClass | 1 | - |