Comparison of vitellogenin responses protein and gene expression of to 4-Nonylphenol in Rockfish (Sebastes schlegeli )

DC Field Value Language
dc.contributor.author 정지현 -
dc.contributor.author R.F.Addsion -
dc.contributor.author 심원준 -
dc.contributor.author 오재룡 -
dc.contributor.author 한창희 -
dc.date.accessioned 2020-07-17T06:52:14Z -
dc.date.available 2020-07-17T06:52:14Z -
dc.date.created 2020-02-11 -
dc.date.issued 2006-05-11 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/31102 -
dc.description.abstract To investigate the in vivo estrogenic activity of 4-Nonylphenol (4-NP) on reproductive function, we have measured the expression level of rockfish vitellogenin (rVTG) mRNA, concentration of plasma VTG and levels of plasma estradiol-17b (E2) and testosterone (T) by radioimmunoassay (RIA). The level of rVTG mRNA expression was increased at 48 h after injection with 4-NP of 10 mg/kg b.w. and after injection in both male and female rockfish. The level of rVTG mRNA expression was increased at 24 h after injection in male rockfish injected with 4-NP of 25 mg/kg b.w., whereas the level of rVTG mRNA expression was increased at 12 h after injection in female injected with same dosage. Concentrations of plasma rVTG in female and male injected with 4 -NP of 10 mg/kg b.w. and 25 mg/kg b.w. were increased at 72 h after injection. Plasma concentrations of T and E2 in female and male injected with 4-NP were not significantly different between two dosages of 10 mg/kg b.w. and 25 mg/kg b.w. These results suggest that 4-NP may disrupt the reproductive system of immature rockfish by acting directly on vitellogenesis. Immature females injected with 4-NP were more sensitive than immature males. -
dc.description.uri 1 -
dc.language English -
dc.publisher SETAC Europe -
dc.relation.isPartOf setac -
dc.title Comparison of vitellogenin responses protein and gene expression of to 4-Nonylphenol in Rockfish (Sebastes schlegeli ) -
dc.type Conference -
dc.citation.endPage 212 -
dc.citation.startPage 212 -
dc.citation.title setac -
dc.contributor.alternativeName 정지현 -
dc.contributor.alternativeName 심원준 -
dc.contributor.alternativeName 오재룡 -
dc.identifier.bibliographicCitation setac, pp.212 -
dc.description.journalClass 1 -
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