Differential gene expression induced by heavy metal in marine medaka, Oryzias javanicus
DC Field | Value | Language |
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dc.contributor.author | 우선옥 | - |
dc.contributor.author | 염승식 | - |
dc.contributor.author | 이택견 | - |
dc.date.accessioned | 2020-07-17T05:30:58Z | - |
dc.date.available | 2020-07-17T05:30:58Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2006-11-06 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/30771 | - |
dc.description.abstract | A metallothionein (MT) gene was isolated for the first time from Javanese medaka, Oryzias javanicus, which shows high adaptability from freshwater to seawater. The full-length cDNA of MT from O. javanicus (OjaMT) comprises 349 bp, excluding the poly(A)+ stretch, and codes for a total of 60 amino acids. The positions of cysteine residues are highly conserved. The pattern of OjaMT expression induced by six heavy metals was analyzed by real-time quantitative PCR. The level of hepatic OjaMT mRNA was increased in a dose-dependent manner by Ag, Cd, Cu, and Zn after 24 h of exposure. However, after Cr and Ni exposure, a significant decrease in OjaMT levels was observed. Cadmium-induced OjaMT expression was detectable in fishes as young as 3 months. After Cd exposure, OjaMT induction was prominent in intestine and liver and moderate in muscle and gill. OjaMT mRNA levels could represent a good biomarker for monitoring heavy metals in seawater. | - |
dc.description.uri | 2 | - |
dc.language | English | - |
dc.publisher | 대한독성유전단백체학회 | - |
dc.relation.isPartOf | 2006 대한독성유전단백체학회 국제학술대회 | - |
dc.title | Differential gene expression induced by heavy metal in marine medaka, Oryzias javanicus | - |
dc.type | Conference | - |
dc.citation.conferencePlace | JA | - |
dc.citation.endPage | 398 | - |
dc.citation.startPage | 398 | - |
dc.citation.title | 2006 대한독성유전단백체학회 국제학술대회 | - |
dc.contributor.alternativeName | 우선옥 | - |
dc.contributor.alternativeName | 염승식 | - |
dc.contributor.alternativeName | 이택견 | - |
dc.identifier.bibliographicCitation | 2006 대한독성유전단백체학회 국제학술대회, pp.398 | - |
dc.description.journalClass | 2 | - |