Discovery of Bioactive Secondary Metabolites from Marine Actinomycetes

Title
Discovery of Bioactive Secondary Metabolites from Marine Actinomycetes
Author(s)
신희재; 유병철; 이정수; 한종우; 이희승
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2007-10-17
Abstract
There is tremendous potential for the isolation of novel bioactive metabolites from marine microorganisms. From the marine samples such as deep sea and shallow water sediments, plants and invertebrates, more than 4,000 strains of marine-derived actinomycetes were isolated. These marine actinomycetes produce different types of new secondary metabolites. We have established that about 10% of isolates show some bioactivity in our assays such as cytotoxicity, antimicrobial, antifungal, and enzyme inhibitory activities and many of the metabolites from marine actinomycetes have the potential to be developed as therapeutic agents. Marine actinomycetes are a prolific but underexploited source for the discovery of novel bioactive metabolites.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/30296
Bibliographic Citation
Asian Symposium for Pharmaceutical Science in JSPS Asian Core Program, pp.169 - 172, 2007
Publisher
Nagasaki International University
Type
Conference
Language
English
Publisher
Nagasaki International University
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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