Thermococcus onnurineus NA1: a Lithoheterotroph as Revealed by Genome Analysis

Title
Thermococcus onnurineus NA1: a Lithoheterotroph as Revealed by Genome Analysis
Author(s)
이현숙; 강성균; 배승섭; 임재규; 이정현; 김윤재; 전정호; 차선신; 권개경; 김상진
KIOST Author(s)
Lee, Hyun Sook(이현숙)Kang, Sung Gyun(강성균)Lee, Jung Hyun(이정현)Kwon, Kae Kyoung(권개경)
Publication Year
2008-05-15
Abstract
A Lithoheterotroph pathway of hyperthermophilic marine archaea Thermococcus onnurineus was revealed by Genome Analysis. To provide some insight into factors that contributed to the apparent successful competition of Thermococcus spp. in hydrothermal vent fields, the genome sequence of T. onnurineus NA1 was determined by combining random whole-genome shotgun sequencing with pyrosequencing. As a result, it was revealed that T. onnurineus NA1 has a single circular chromosome (1,847,607 bp) without any exochromosomal elemnets, and a total of 1,976 coding DNA sequences (CDSs) were identified. Synteny comparison by blastp-all-va-all between T. onnurineus NA1 and other Thermococcales strains confirmed the high frequency of DNA rearrangement. The gene rearrangement between T.onnurineus NA1 and T. kodakaraensis KOD1 seemed to take place at the level of chromosomal segments, confirming more close phylogenetic relationship than to other Pyrococcus strains. Interestingly, we found that T. onnurineus NA1 retained the metabolic pathways not only for organotrophic growth but also for lithotrophic growth by analyzing the genome sequence.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/30045
Bibliographic Citation
the 48th MSK Annual Meetion and 2008 international Symposium on Microbiology, pp.119 - 120, 2008
Publisher
한국미생물학회
Type
Conference
Language
English
Publisher
한국미생물학회
Related Researcher
Research Interests

marine biotechnology,molecular microbiology,해양생명공학,분자미생물학

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