Thermococcus onnurineus NA1의 유전체분석 연구
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Title
- Thermococcus onnurineus NA1의 유전체분석 연구
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Alternative Title
- The Complete Genome Sequence of Thermococcus onnurineus NA1 Reveals a Mixed Heterotrophic and Carboxydotrophic Metabolism
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Author(s)
- 강성균; 이현숙; 배승섭; 김윤재; 김상진; 이정현
- KIOST Author(s)
- Kang, Sung Gyun(강성균); Lee, Hyun Sook(이현숙); Kim, Yun Jae(김윤재); Lee, Jung Hyun(이정현)
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Alternative Author(s)
- 강성균; 이현숙; 배승섭; 김윤재; 김상진; 이정현
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Publication Year
- 2008-09-01
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Abstract
- Members of the genus Thermococcus, sulfur-reducing hyperthermophilic archaea, are ubiquitously present in various deep-sea hydrothermal vent systems and are considered to play a significant role in the microbial consortia. We present the complete genome sequence and feature analysis of Thermococcus onnurineus NA1 isolated from a deep-sea hydrothermal vent area, which reveal clues to its physiology. Based on results of genomic analysis, T. onnurineus NA1 possesses the metabolic pathways for organotrophic growth on peptides, amino acids, or sugars. More interesting was the discovery that the genome encoded unique proteins that are involved in carboxydotrophy to generate energy by oxidation of CO to CO2, thereby providing a mechanistic basis for growth with CO as substrate. This lithotrophic feature in combination with carbon fixation via RuBisCO introduces a new strategy with a complementing energy supply for T. onnurineus NA1 potentially allowing it to cope with nutrient stress in the surrounding of hydrothermal vents, providing the first genomic evidence for the carboxydotrophy in Thermococcus.
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/29827
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Bibliographic Citation
- Extremophile 2008, pp.134, 2008
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Publisher
- Internation Society of Extremophile
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Type
- Conference
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Language
- English
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