Antibacterial activities of halogenated bis(hydroxyphenyl)methanes
DC Field | Value | Language |
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dc.contributor.author | 이희승 | - |
dc.contributor.author | 신희재 | - |
dc.contributor.author | K.-B. Oh | - |
dc.date.accessioned | 2020-07-16T22:31:45Z | - |
dc.date.available | 2020-07-16T22:31:45Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2009-06-25 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/29395 | - |
dc.description.abstract | Biologically active bromophenols were isolated from red alga Odonthalia corymbifera. And a series of modified halophenols was prepared by the reaction of bis(hydroxyphenyl)methanes with effective halogenating agents such as bromine, sulfuryl chloride, and xenon fluoride. One of these compounds, a bromophenol, 2,2',3,3'-tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, .frequently isolated from red algae, was synthesized for the first time. Other halophenols included several novel compounds were synthesized from the phenolic intermediates, bis(3,4-dihydroxyphenyl)methane and bis(2-hydroxyphenyl)methane. All of these halophenols were tested for antibacterial activity against three Gram-positive, three Gram-negative bacteria. Of all these halophenols, 3,3',5,5'-tetrachloro-2,2'-dihydroxydiphenylmethane exerted a powerful antibacterial effect against Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Proteus vulgaris, and Salmonella typhimurium. The preliminary structure–activity relationship will be described. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | Tetrahedron Symposium | - |
dc.title | Antibacterial activities of halogenated bis(hydroxyphenyl)methanes | - |
dc.type | Conference | - |
dc.citation.endPage | C031 | - |
dc.citation.startPage | C031 | - |
dc.citation.title | Tetrahedron Symposium | - |
dc.contributor.alternativeName | 이희승 | - |
dc.contributor.alternativeName | 신희재 | - |
dc.identifier.bibliographicCitation | Tetrahedron Symposium, pp.C031 | - |
dc.description.journalClass | 1 | - |