Aquatic Environment Health Assessment-the Ecotoxicogenomic Challenges

Title
Aquatic Environment Health Assessment-the Ecotoxicogenomic Challenges
Author(s)
염승식
KIOST Author(s)
Yum, Seung Shic(염승식)
Publication Year
2009-09-23
Abstract
During the last two decades, the knowledge on gene structure and function, enormous amount of nucleotide sequence information have accumulated due to the remarkable advances in molecular biology. These advances make it possible to evaluate the biological responses against environmental changes at subcelluar level by genomewide gene expression analysis for prognostic risk assessment, namely environmental genetic toxicology or called as ‘Ecotoxicogenomics’. The field of ecotoxicogenomics is rapidly growing and proof-of-principle studies are urgently needed to assess the potential of genomics technologies in ecotoxicology. However, almost all the organisms in nature are less traditional model systems and genomewide gene expression data are not available. To overcome the limitation, several challenges (e.g., differential display PCR, subtractive cDNA library construction, heterologous hybridization, and target gene isolation) have been carried out. In this presentation, four topics; 1) new marine test fish development, 2) environmental stress responsive gene isolation in soft coral, 3) differential gene expression in red alga, 4) phenotype changes in hydra regarding to positional value alteration; following the strategies above mentioned will be discussed. Finally, the ‘Ecoepigenetics’ a new approach for accessing environmental changes will also be introduced.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/29340
Bibliographic Citation
The Joint International Symposium of 5th International Conference on Toxicogenomics (ICT) and 2nd Toxicogenomics Integrated Environmental Science (TIES), pp.45, 2009
Publisher
Molecular and Cellular Toxicology
Type
Conference
Language
English
Publisher
Molecular and Cellular Toxicology
Related Researcher
Research Interests

Marine Genomics,Environmental Genomics,Novel biomaterials,해양생물유전체,생태환경유전체,바이오신소재

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