Minke whale genome and aquatic adaptation in cetaceans SCIE SCOPUS

Cited 147 time in WEB OF SCIENCE Cited 144 time in Scopus
Title
Minke whale genome and aquatic adaptation in cetaceans
Author(s)
Yim, Hyung-Soon; Cho, Yun Sung; Guang, Xuanmin; Kang, Sung Gyun; Jeong, Jae-Yeon; Cha, Sun-Shin; Oh, Hyun-Myung; Lee, Jae-Hak; Yang, Eun Chan; Kwon, Kae Kyoung; Kim, Yun Jae; Kim, Tae Wan; Kim, Wonduck; Jeon, Jeong Ho; Kim, Sang-Jin; Choi, Dong Han; Jho, Sungwoong; Kim, Hak-Min; Ko, Junsu; Kim, Hyunmin; Shin, Young-Ah; Jung, Hyun-Ju; Zheng, Yuan; Wang, Zhuo; Chen, Yan; Chen, Ming; Jiang, Awei; Li, Erli; Zhang, Shu; Hou, Haolong; Kim, Tae Hyung; Yu, Lili; Liu, Sha; Ahn, Kung; Cooper, Jesse; Park, Sin-Gi; Hong, Chang Pyo; Jin, Wook; Kim, Heui-Soo; Park, Chankyu; Lee, Kyooyeol; Chun, Sung; Morin, Phillip A.; O'Brien, Stephen J.; Lee, Hang; Kimura, Jumpei; Moon, Dae Yeon; Manica, Andrea; Edwards, Jeremy; Kim, Byung Chul; Kim, Sangsoo; Wang, Jun; Bhak, Jong; Lee, Hyun Sook; Lee, Jung-Hyun
KIOST Author(s)
Yim, Hyung Soon(임형순)Kang, Sung Gyun(강성균)Yang, Eun Chan(양은찬)Kwon, Kae Kyoung(권개경)Choi, Dong Han(최동한)Lee, Hyun Sook(이현숙)Lee, Jung Hyun(이정현)
Publication Year
2014-01
Abstract
The shift from terrestrial to aquatic life by whales was a substantial evolutionary event. Here we report the whole-genome sequencing and de novo assembly of the minke whale genome, as well as the whole-genome sequences of three minke whales, a fin whale, a bottlenose dolphin and a finless porpoise. Our comparative genomic analysis identified an expansion in the whale lineage of gene families associated with stress-responsive proteins and anaerobic metabolism, whereas gene families related to body hair and sensory receptors were contracted. Our analysis also identified whale-specific mutations in genes encoding antioxidants and enzymes controlling blood pressure and salt concentration. Overall the whale-genome sequences exhibited distinct features that are associated with the physiological and morphological changes needed for life in an aquatic environment, marked by resistance to physiological stresses caused by a lack of oxygen, increased amounts of reactive oxygen species and high salt levels.
ISSN
1061-4036
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/2919
DOI
10.1038/ng.2835
Bibliographic Citation
NATURE GENETICS, v.46, no.1, pp.88 - +, 2014
Publisher
NATURE PUBLISHING GROUP
Type
Article
Language
English
Document Type
Article
Publisher
NATURE PUBLISHING GROUP
Related Researcher
Research Interests

marine biotechnology,molecular microbiology,해양생명공학,분자미생물학

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