Minke whale genome and aquatic adaptation in cetaceans
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Title
- Minke whale genome and aquatic adaptation in cetaceans
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Author(s)
- Yim, Hyung-Soon; Cho, Yun Sung; Guang, Xuanmin; Kang, Sung Gyun; Jeong, Jae-Yeon; Cha, Sun-Shin; Oh, Hyun-Myung; Lee, Jae-Hak; Yang, Eun Chan; Kwon, Kae Kyoung; Kim, Yun Jae; Kim, Tae Wan; Kim, Wonduck; Jeon, Jeong Ho; Kim, Sang-Jin; Choi, Dong Han; Jho, Sungwoong; Kim, Hak-Min; Ko, Junsu; Kim, Hyunmin; Shin, Young-Ah; Jung, Hyun-Ju; Zheng, Yuan; Wang, Zhuo; Chen, Yan; Chen, Ming; Jiang, Awei; Li, Erli; Zhang, Shu; Hou, Haolong; Kim, Tae Hyung; Yu, Lili; Liu, Sha; Ahn, Kung; Cooper, Jesse; Park, Sin-Gi; Hong, Chang Pyo; Jin, Wook; Kim, Heui-Soo; Park, Chankyu; Lee, Kyooyeol; Chun, Sung; Morin, Phillip A.; O'Brien, Stephen J.; Lee, Hang; Kimura, Jumpei; Moon, Dae Yeon; Manica, Andrea; Edwards, Jeremy; Kim, Byung Chul; Kim, Sangsoo; Wang, Jun; Bhak, Jong; Lee, Hyun Sook; Lee, Jung-Hyun
- KIOST Author(s)
- Yim, Hyung Soon(임형순); Kang, Sung Gyun(강성균); Yang, Eun Chan(양은찬); Kwon, Kae Kyoung(권개경); Kim, Yun Jae(김윤재); Choi, Dong Han(최동한); Lee, Hyun Sook(이현숙); Lee, Jung Hyun(이정현)
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Alternative Author(s)
- 임형순; 강성균; 정재연; 차선신; 오현명; 이재학; 양은찬; 권개경; 김윤재; 김태완; 김원덕; 김상진; 최동한; 이현숙; 이정현
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Publication Year
- 2014-01
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Abstract
- The shift from terrestrial to aquatic life by whales was a substantial evolutionary event. Here we report the whole-genome sequencing and de novo assembly of the minke whale genome, as well as the whole-genome sequences of three minke whales, a fin whale, a bottlenose dolphin and a finless porpoise. Our comparative genomic analysis identified an expansion in the whale lineage of gene families associated with stress-responsive proteins and anaerobic metabolism, whereas gene families related to body hair and sensory receptors were contracted. Our analysis also identified whale-specific mutations in genes encoding antioxidants and enzymes controlling blood pressure and salt concentration. Overall the whale-genome sequences exhibited distinct features that are associated with the physiological and morphological changes needed for life in an aquatic environment, marked by resistance to physiological stresses caused by a lack of oxygen, increased amounts of reactive oxygen species and high salt levels.
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ISSN
- 1061-4036
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/2919
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DOI
- 10.1038/ng.2835
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Bibliographic Citation
- NATURE GENETICS, v.46, no.1, pp.88 - +, 2014
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Publisher
- NATURE PUBLISHING GROUP
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Type
- Article
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Language
- English
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Document Type
- Article
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