Differential expression of Hypoxia-response genes in Mytilus galloprovincialis under experimental conditions

DC Field Value Language
dc.contributor.author 전혜영 -
dc.contributor.author 김보라 -
dc.contributor.author 원효경 -
dc.contributor.author 우선옥 -
dc.contributor.author 염승식 -
dc.date.accessioned 2020-07-16T18:50:17Z -
dc.date.available 2020-07-16T18:50:17Z -
dc.date.created 2020-02-11 -
dc.date.issued 2010-11-04 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/28607 -
dc.description.abstract Marine hypoxia has become one of the major concerns of aquatic environment in the last few decades. Monitoring the biological effects of hypoxia in aquatic system may provide useful data in management of natural aquatic environment. In this study, we investigated the response of the Mytilus galloprovincialis to hypoxia under experimental conditions. Total RNA was extracted using TRIzol® reagent method in gill after 0, 24, 48 and 72 hours exposure to hypoxia. Differential display polymerase chain reaction (DD-PCR) was carried out to identify gene candidates. As a result, we identified 130 differentially expressed genes and 74 genes were up-regulated and 56 genes were down-regulated during the hypoxia. These genes were implicated in the different pathways such as post-translational modification, protein turnover and chaperones; translation, ribosomal structure and biogenesis; signal transduction mechanisms; defense mechanisms; energy production and conversion; cytoskeleton; lipid transport and metabolism; replication, recombination and repair; extracellular structures; general function prediction; and unknown function based on KOG (Orthologous groups for eukaryotic complete genomes) classification. The present study contributes to the identification of many potential genetic biomarkers that could be used in hypoxia monitoring. -
dc.description.uri 1 -
dc.language English -
dc.publisher 대한독성유전단백체학회 -
dc.relation.isPartOf 6th International Conference on Toxicogenomics 2010 -
dc.title Differential expression of Hypoxia-response genes in Mytilus galloprovincialis under experimental conditions -
dc.type Conference -
dc.citation.conferencePlace KO -
dc.citation.endPage 37 -
dc.citation.startPage 37 -
dc.citation.title 6th International Conference on Toxicogenomics 2010 -
dc.identifier.bibliographicCitation 6th International Conference on Toxicogenomics 2010, pp.37 -
dc.description.journalClass 1 -
Appears in Collections:
South Sea Research Institute > Risk Assessment Research Center > 2. Conference Papers
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