EVALUATING THE USE OF INVITRO BIOASSAYS FOR THE ECOTOXICOLOGICAL ASSESSMENT OF MASAN BAY SEDIMENTS IN COMBINATION WITH CHEMICALANALYSES
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Title
- EVALUATING THE USE OF INVITRO BIOASSAYS FOR THE ECOTOXICOLOGICAL ASSESSMENT OF MASAN BAY SEDIMENTS IN COMBINATION WITH CHEMICALANALYSES
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Author(s)
- 정지현; 홍상희; N.Kannan; 임운혁; 심원준
- KIOST Author(s)
- Jung, Jee Hyun(정지현); Hong, Sang Hee(홍상희); Yim, Un Hyuk(임운혁); Shim, Won Joon(심원준)
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Alternative Author(s)
- 정지현; 홍상희; 임운혁; 심원준
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Publication Year
- 2011-11-03
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Abstract
- An assessment methodology combining ecotoxicological and chemical evaluations is described to assess the quality of coastal sediments. Three invitrobioassays,namely,AChE assay, E- assay(+) and CALUX have been performed in order to assess the neurotoxic, estrogenic effects of dioxin-like chemical contamination in Masan Bay sediments. 24 sediment samples have been collected in Masan Bay, Korea a heavily impacted ecosystem because of rapid development in recent years. Spearman correlation coefficient identifies close links between chemical measurement of a toxicant and its biological effects through the bioassays. Significant induced AChE activity was measured at site 12 and 15 where high levels of dioxin-like contaminants were determined as well. Thus CALUX bioassay showed high correlation (R=0.75) with APs, PCDD and PCDFs at sites 12 and 15. Good correlation was obtained for BTs-AChE, CHLs-AChE and APs-AChE, respectively. Significant induction of E-assay was seen at sampling sites 5, 12 and 15. Among CHLs-E-assay (+), Co-PCB-E-assay and DDT-E-assay (+) correlation coefficients of 0.77, 0.77 and 0.65 were obtained respectively. This approach offers an integrated potential of assessing complex matrix such as sediment with multiple contaminant enrichment for further research.
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/28104
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Bibliographic Citation
- International Symposium Pollutant Responses in Marine Organism (PRIMO), pp.1 - 2, 2011
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Publisher
- International
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Type
- Conference
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Language
- English
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