Changes in gene expression profile of marine medaka fish with acute toxicity of 4-Nonylphenol
DC Field | Value | Language |
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dc.contributor.author | 원효경 | - |
dc.contributor.author | 우선옥 | - |
dc.contributor.author | 이애경 | - |
dc.contributor.author | 염승식 | - |
dc.date.accessioned | 2020-07-16T11:30:22Z | - |
dc.date.available | 2020-07-16T11:30:22Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2012-11-02 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/27432 | - |
dc.description.abstract | Differential gene expression profiling was performed with a cDNA microarray in the liver tissue of the marine medaka fish, Oryzias javanicus, after exposure to 4-Nonylphenol which is used for detergents, pesticides, anti-oxidants in plastics and rubbers. One hundred ninety-five differentially expressed candidate genes were identified. The expression of 107 genes was up-regulated and that of 88 genes was down-regulated. These genes are associated with the Information storage and processing (Translation, ribosomal structure and biogenesis, J; RNA processing and modification, A; Transcription, K; Replication, recombination and repair, L; Chromatin structure and dynamics, B), Cellular processes and signaling (Cell cycle control, cell division, chromosome partitioning, D; Defense mechanisms, V; Signal transduction mechanisms, T; Cell wall/membrane/envelope biogenesis, M; Cytoskeleton, Z; Extracellular structures, W; Intracellular trafficking, secretion, and vesicular transport, U; Posttranslational modification, protein turnover, chaperones, O), Metabolism (Energy production and conversion, C; Carbohydrate transport and metabolism, G; Amino acid transport and metabolism, E; Nucleotide transport and metabolism, F; Coenzyme transport and metabolism, H; Lipid transport and metabolism, I; Inorganic ion transport and metabolism, P; Secondary metabolites biosynthesis, transport and catabolism, Q), Postics and rubbers. One hundred ninety-five differentially expressed candidate genes were identified. The expression of 107 genes was up-regulated and that of 88 genes was down-regulated. These genes are associated with the Information storage and processing (Translation, ribosomal structure and biogenesis, J; RNA processing and modification, A; Transcription, K; Replication, recombination and repair, L; Chromatin structure and dynamics, B), Cellular processes and signaling (Cell cycle control, cell division, chromosome partitioning, D; Defens | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | 대한독성유전단백체학회 | - |
dc.relation.isPartOf | 8th ICT (International Conference on Toxicogenomics) | - |
dc.title | Changes in gene expression profile of marine medaka fish with acute toxicity of 4-Nonylphenol | - |
dc.type | Conference | - |
dc.citation.conferencePlace | KO | - |
dc.citation.endPage | 36 | - |
dc.citation.startPage | 36 | - |
dc.citation.title | 8th ICT (International Conference on Toxicogenomics) | - |
dc.contributor.alternativeName | 원효경 | - |
dc.contributor.alternativeName | 우선옥 | - |
dc.contributor.alternativeName | 이나윤 | - |
dc.contributor.alternativeName | 염승식 | - |
dc.identifier.bibliographicCitation | 8th ICT (International Conference on Toxicogenomics), pp.36 | - |
dc.description.journalClass | 1 | - |