Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill SCIE SCOPUS

Cited 37 time in WEB OF SCIENCE Cited 40 time in Scopus
Title
Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill
Author(s)
Hong, Seongjin; Lee, Sangwoo; Choi, Kyungho; Kim, Gi Beum; Ha, Sung Yong; Kwon, Bong-Oh; Ryu, Jongseong; Yim, Un Hyuk; Shim, Won Joon; Jung, Jinho; Giesy, John P.; Khim, Jong Seong
KIOST Author(s)
Ha, Sung Yong(하성용)Yim, Un Hyuk(임운혁)Shim, Won Joon(심원준)
Publication Year
2015-04
Abstract
The major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained similar to 18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites. (C) 2015 Elsevier Ltd. All rights reserved.
ISSN
0269-7491
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/2510
DOI
10.1016/j.envpol.2015.01.009
Bibliographic Citation
ENVIRONMENTAL POLLUTION, v.199, pp.110 - 118, 2015
Publisher
ELSEVIER SCI LTD
Subject
POLYCYCLIC AROMATIC-HYDROCARBONS; IN-VITRO BIOASSAY; INTERTIDAL SEDIMENTS; RELATIVE POTENCIES; MARINE-SEDIMENTS; TOXIC EVENTS; IDENTIFICATION; KOREA; ENVIRONMENT; RESPONSES
Keywords
Polycyclic aromatic hydrocarbons; Effect-directed analysis; H4IIE-luc bioassay; Oil weathering; Sediments; Yellow Sea
Type
Article
Language
English
Document Type
Article
Publisher
ELSEVIER SCI LTD
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