Bile Acids from a Marine Sponge-Associated Fungus Penicillium sp. 108YD020

DC Field Value Language
dc.contributor.author 필감방 -
dc.contributor.author 이화선 -
dc.contributor.author 최병규 -
dc.contributor.author 이희승 -
dc.contributor.author 이종석 -
dc.contributor.author 이연주 -
dc.contributor.author 이지훈 -
dc.contributor.author 신희재 -
dc.date.accessioned 2020-07-15T21:52:52Z -
dc.date.available 2020-07-15T21:52:52Z -
dc.date.created 2020-02-11 -
dc.date.issued 2016-04-22 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/24861 -
dc.description.abstract Bile acids are principal ingredients of bile synthesized in the liver of vertebrates such as mammals and fish, and secreted into the duodenum to play an important role in lipid metabolism. They include cholic acid (CA), chenocholic acid (CCA), deoxycholic acid (DCA) and their conjugates with glycine and taurine, which contribute to bile formation. A variety of bile acids have a steroid skeleton and carboxylic side chain. In addition, bile acids have been reported that they are different in the number and substituted position of the hydroxyl group and side chain length. The strain 108YD020 was isolated as various bile acid-producing microorganism from a marine sponge collected at Wangdolcho, East sea, Korea and identified as Penicillium sp. We obtained six bile acid derivatives and their structures were determined by the analysis of 1D, 2D NMR and LC-MS data, along with chemical methods and literature data analysis. This is the first report on the bile acids from marine fungi.A), deoxycholic acid (DCA) and their conjugates with glycine and taurine, which contribute to bile formation. A variety of bile acids have a steroid skeleton and carboxylic side chain. In addition, bile acids have been reported that they are different in the number and substituted position of the hydroxyl group and side chain length. The strain 108YD020 was isolated as various bile acid-producing microorganism from a marine sponge collected at Wangdolcho, East sea, Korea and identified as Penicillium sp. We obtained six bile acid derivatives and their structures were determined by the analysis of 1D, 2D NMR and LC-MS data, along with chemical methods and literature data analysis. This is the first report on the bile acids from marine fungi. -
dc.description.uri 2 -
dc.language English -
dc.publisher 한국생물공학회 -
dc.relation.isPartOf 한국생물공학회 -
dc.title Bile Acids from a Marine Sponge-Associated Fungus Penicillium sp. 108YD020 -
dc.type Conference -
dc.citation.conferencePlace KO -
dc.citation.endPage 127 -
dc.citation.startPage 127 -
dc.citation.title 한국생물공학회 -
dc.identifier.bibliographicCitation 한국생물공학회, pp.127 -
dc.description.journalClass 2 -
Appears in Collections:
Marine Resources Research Division > Marine Biotechnology Research Center > 2. Conference Papers
Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse