Stellettapeptins A and B, HIV-inhibitory cyclic depsipeptides from the marine sponge Stelletta sp. SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Shin, H.J. | - |
dc.contributor.author | Rashid, M.A. | - |
dc.contributor.author | Cartner, L.K. | - |
dc.contributor.author | Bokesch, H.R. | - |
dc.contributor.author | Wilson, J.A. | - |
dc.contributor.author | McMahon, J.B. | - |
dc.contributor.author | Gustafson, K.R. | - |
dc.date.accessioned | 2020-04-20T03:40:11Z | - |
dc.date.available | 2020-04-20T03:40:11Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2015-06 | - |
dc.identifier.issn | 0040-4039 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/2469 | - |
dc.description.abstract | Two new HIV-inhibitory depsipeptides, stellettapeptins A (1) and B (2), were isolated from an extract of the marine sponge Stelletta sp., collected from northwestern Australia. Structures of these cyclic nonribosomal peptides were elucidated on the basis of extensive NMR data analysis, and chemical degradation and derivatization studies. Stellettapeptins contain numerous nonproteinogenic amino acid residues and they are the first peptides reported to contain a 3-hydroxy-6,8-dimethylnon-4-(Z)-enoic acid moiety. Compounds 1 and 2 potently inhibit infection of human T-lymphoblastoid cells by HIV-1RF with EC50 values of 23 and 27 nM, respectively. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | Elsevier Ltd | - |
dc.title | Stellettapeptins A and B, HIV-inhibitory cyclic depsipeptides from the marine sponge Stelletta sp. | - |
dc.type | Article | - |
dc.citation.endPage | 4219 | - |
dc.citation.startPage | 4215 | - |
dc.citation.title | Tetrahedron Letters | - |
dc.citation.volume | 56 | - |
dc.citation.number | 28 | - |
dc.contributor.alternativeName | 신희재 | - |
dc.identifier.bibliographicCitation | Tetrahedron Letters, v.56, no.28, pp.4215 - 4219 | - |
dc.identifier.doi | 10.1016/j.tetlet.2015.05.058 | - |
dc.identifier.scopusid | 2-s2.0-84930926584 | - |
dc.identifier.wosid | 000356757200016 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordPlus | Stelletta | - |
dc.subject.keywordPlus | Human immunodeficiency virus 1 | - |
dc.subject.keywordPlus | Stelletta | - |
dc.subject.keywordPlus | data analysis | - |
dc.subject.keywordPlus | degradation | - |
dc.subject.keywordPlus | derivatization | - |
dc.subject.keywordPlus | EC50 | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | human cell | - |
dc.subject.keywordPlus | Human immunodeficiency virus 1 | - |
dc.subject.keywordPlus | Human immunodeficiency virus 1 infection | - |
dc.subject.keywordPlus | IC50 | - |
dc.subject.keywordPlus | lymphoblastoid cell | - |
dc.subject.keywordPlus | marine species | - |
dc.subject.keywordPlus | nuclear magnetic resonance | - |
dc.subject.keywordPlus | proton nuclear magnetic resonance | - |
dc.subject.keywordPlus | 3 hydroxy 6,8 dimethylnon 4 enoic acid | - |
dc.subject.keywordPlus | amino acid | - |
dc.subject.keywordPlus | cyclodepsipeptide | - |
dc.subject.keywordPlus | stellettapeptin A | - |
dc.subject.keywordPlus | stellettapeptin B | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | amino acid sequence | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | cell viability assay | - |
dc.subject.keywordPlus | cytopathogenic effect | - |
dc.subject.keywordPlus | cytotoxicity | - |
dc.subject.keywordAuthor | Anti-HIV | - |
dc.subject.keywordAuthor | Depsipeptide | - |
dc.subject.keywordAuthor | Sponge peptide | - |
dc.subject.keywordAuthor | Stelletta | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |