Transcriptional responses and prediction of metabolic changes in marine medaka fish (Oryzias javanicus) to acute exposure to endocrine disrupting chemicals

DC Field Value Language
dc.contributor.author 조예진 -
dc.contributor.author 이나영 -
dc.contributor.author 이나윤 -
dc.contributor.author 염승식 -
dc.date.accessioned 2020-07-15T19:33:56Z -
dc.date.available 2020-07-15T19:33:56Z -
dc.date.created 2020-02-11 -
dc.date.issued 2016-11-02 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/24398 -
dc.description.abstract The differentially expressed genes in the liver tissue of the marine medaka fish, Oryzias javanicus, were profiled using an oligo-microarray (EnviHaz-Fish Array) which contains oligonucleotide probes for 22,796 unigenes of O. javanicus, after the fish were exposed to five kinds of endocrine disrupting chemicals (EDCs), bisphenol A (BPA), 17β-estradiol (E2), nonylphenol (NP), perfluorooctanesulfonate (PFOS), and triclosan (TCS) for 12, 24, 48, or 72 h to predict the metabolic and physiological changes with exposure time. The transcriptomic changes were highly dynamic in the EDC-exposed fish groups by the exposure time. The differentially expressed genes were used to predict the changes that occurred in the metabolic pathways and processes in response to EDCs exposure.er the fish were exposed to five kinds of endocrine disrupting chemicals (EDCs), bisphenol A (BPA), 17β-estradiol (E2), nonylphenol (NP), perfluorooctanesulfonate (PFOS), and triclosan (TCS) for 12, 24, 48, or 72 h to predict the metabolic and physiological changes with exposure time. The transcriptomic changes were highly dynamic in the EDC-exposed fish groups by the exposure time. The differentially expressed genes were used to predict the changes that occurred in the metabolic pathways and processes in response to EDCs exposure. -
dc.description.uri 1 -
dc.language English -
dc.publisher 2016 -
dc.relation.isPartOf 2016 대한환경위해성보건과학회 국제학술대회 -
dc.title Transcriptional responses and prediction of metabolic changes in marine medaka fish (Oryzias javanicus) to acute exposure to endocrine disrupting chemicals -
dc.type Conference -
dc.citation.conferencePlace KO -
dc.citation.endPage 36 -
dc.citation.startPage 36 -
dc.citation.title 2016 대한환경위해성보건과학회 국제학술대회 -
dc.contributor.alternativeName 조예진 -
dc.contributor.alternativeName 이나영 -
dc.contributor.alternativeName 이나윤 -
dc.contributor.alternativeName 염승식 -
dc.identifier.bibliographicCitation 2016 대한환경위해성보건과학회 국제학술대회, pp.36 -
dc.description.journalClass 1 -
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South Sea Research Institute > Risk Assessment Research Center > 2. Conference Papers
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