Anti-oxidant Effects of Secondary Metabolites from the Marine Fungus Penicillium sp. 168CLC-17.1

Title
Anti-oxidant Effects of Secondary Metabolites from the Marine Fungus Penicillium sp. 168CLC-17.1
Author(s)
최병규; Phan Thi Hoei Trinh; Tran Thi Thanh Van; 신희재
KIOST Author(s)
Choi, Byeoung Kyu(최병규)
Publication Year
2019-04-18
Abstract
The marine environment has played a significant reservoir of natural products for new drugs over the last few decades. The majority of novel secondary metabolites from the ocean have structural diversities and potent bioactivities. Marine-derived microorganisms, especially marine fungi, are considered as a novel source in the biological and chemical fields. Moreover, many natural products from marine fungi were developed as medicines and are being studied to cure diverse diseases and infections. The fungus 168CLC-17.1 was isolated from a sediment sample, collected at Cu Lao Cham island, Quang Nam, Vietnam by modified Sabouraud medium and identified as Penicillium janthinellum. From the strain, a p-terpehenyl derivative, emodin and aflavinin were isolated from the EtOAc extract. Their structures were determined by MS, 1D and 2D NMR data analyses. All compounds were tested for anti-oxidant capacities using ABTS, DPPH and ORAC assays. Among them, 3,3’’-dihydroxy-6’-desmethylterphenyllin (1) showed potent anti-oxidant activities.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/22771
Bibliographic Citation
Korean Chemical Society, pp.135, 2019
Publisher
Korean Chemical Society
Type
Conference
Language
English
Publisher
Korean Chemical Society
Related Researcher
Research Interests

Marine natural product,Marine microorganisms,해양천연물,해양미생물

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