Skin whitening and anti-corrugation activities of glycoprotein fractions from liquid extracts of boiled sea cucumber SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Kim, So Jung | - |
dc.contributor.author | Park, So Yun | - |
dc.contributor.author | Hong, Sun-Mee | - |
dc.contributor.author | Kwon, Eun-Hye | - |
dc.contributor.author | Lee, Taek-Kyun | - |
dc.date.accessioned | 2020-04-20T02:25:39Z | - |
dc.date.available | 2020-04-20T02:25:39Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 1995-7645 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/2152 | - |
dc.description.abstract | Objective: To determine skin whitening and wrinkle improvement efficacy, glycoprotein fractions were extracted from liquid extracts of boiled sea cucumber and their effects on tyrosine and elastase inhibitory activities were assayed. Methods: Fractions above and below 50 kDa (>50 kDa and <50 kDa) were extracted via a series of steps invovling: boiling, filtering, desalting and freeze drying. Cytotoxicity, skin whitening and wrinkle-removing effects of boiled liquid were determined. Results: Our MTT data showed that neither glycoprotein fraction of boiled liquid induces cellular cytotoxicity up to a concentration of 10 mg/mL treatment of the mouse melanoma cell line, B16F10, with 10 mg/mL >50 kDa enhanced tyrosinase and clastase inhibitory activities by 50.84% and 28.78%, respectively. Correlations of the >50 kDa concentration with tyrosinase inhibitory (R-2=0.968) and elastase inhibitory (R-2=0.983) efficacy were significant. Conclusions: >50 kDa glycoprotein fraction isolated from liquid extracts of boiled sea cucumber, which can serve as a functional cosmetic ingredient for whitening and wrinkle improvement of skin. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | FUCOSYLATED CHONDROITIN SULFATE | - |
dc.subject | ISOSTICHOPUS-BADIONOTUS | - |
dc.subject | APOSTICHOPUS-JAPONICUS | - |
dc.subject | TRITERPENE GLYCOSIDES | - |
dc.subject | INHIBITORY-ACTIVITY | - |
dc.subject | ANTIOXIDANT | - |
dc.subject | POLYSACCHARIDES | - |
dc.subject | ANTICOAGULANT | - |
dc.subject | TYROSINASE | - |
dc.subject | DIGESTION | - |
dc.title | Skin whitening and anti-corrugation activities of glycoprotein fractions from liquid extracts of boiled sea cucumber | - |
dc.type | Article | - |
dc.citation.endPage | 984 | - |
dc.citation.startPage | 980 | - |
dc.citation.title | ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE | - |
dc.citation.volume | 9 | - |
dc.citation.number | 10 | - |
dc.contributor.alternativeName | 박소윤 | - |
dc.contributor.alternativeName | 이택견 | - |
dc.identifier.bibliographicCitation | ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, v.9, no.10, pp.980 - 984 | - |
dc.identifier.doi | 10.1016/j.apjtm.2016.08.001 | - |
dc.identifier.scopusid | 2-s2.0-84994152170 | - |
dc.identifier.wosid | 000382895900013 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | FUCOSYLATED CHONDROITIN SULFATE | - |
dc.subject.keywordPlus | ISOSTICHOPUS-BADIONOTUS | - |
dc.subject.keywordPlus | APOSTICHOPUS-JAPONICUS | - |
dc.subject.keywordPlus | TRITERPENE GLYCOSIDES | - |
dc.subject.keywordPlus | INHIBITORY-ACTIVITY | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | POLYSACCHARIDES | - |
dc.subject.keywordPlus | ANTICOAGULANT | - |
dc.subject.keywordPlus | TYROSINASE | - |
dc.subject.keywordPlus | DIGESTION | - |
dc.subject.keywordAuthor | Sea cucumber | - |
dc.subject.keywordAuthor | Glycoprotein | - |
dc.subject.keywordAuthor | Cytotoxicity | - |
dc.subject.keywordAuthor | Tyrosinase | - |
dc.subject.keywordAuthor | Elastase | - |
dc.relation.journalWebOfScienceCategory | Public, Environmental & Occupational Health | - |
dc.relation.journalWebOfScienceCategory | Tropical Medicine | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Public, Environmental & Occupational Health | - |
dc.relation.journalResearchArea | Tropical Medicine | - |