Paper Spray Chemical Ionization: Highly Sensitive Ambient Ionization Method for Low- and Nonpolar Aromatic Compounds SCIE SCOPUS

Cited 22 time in WEB OF SCIENCE Cited 22 time in Scopus
Title
Paper Spray Chemical Ionization: Highly Sensitive Ambient Ionization Method for Low- and Nonpolar Aromatic Compounds
Author(s)
Kim, Donghwi; Yim, Un Hyuk; Kim, Byungjoo; Cha, Sangwon; Kim, Sunghwan
KIOST Author(s)
Kim, Dong Hwi(김동휘)Yim, Un Hyuk(임운혁)
Publication Year
2017-09
Abstract
Sensitivity is an important factor determining successful mass spectrometry (MS) analysis of metabolome, protein, drugs, and environmental samples. Currently, nano-electrospray ionization (ESI) is widely used as a sensitive ionization method. However, application of nano-ESI is limited to polar molecules and there is no atmospheric pressure ionization technique developed that can be used for MS analysis of low- and nonpolar compounds with sensitivity that can match with nano-ESI. Herein, we propose paper spray chemical ionization (PSCI) as an ionization technique that can be used to analyze low- and nonpolar aromatic compounds with high sensitivity. PSCI is based on paper spray ionization utilizing corona discharge phenomenon. PSCI can sensitively and quantitatively detect down to picogram (or femtomole) levels of low and nonpolar aromatic compounds.
ISSN
0003-2700
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/1152
DOI
10.1021/acs.analchem.7b01733
Bibliographic Citation
ANALYTICAL CHEMISTRY, v.89, no.17, pp.9056 - 9061, 2017
Publisher
AMER CHEMICAL SOC
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
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