Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill SCIE SCOPUS

DC Field Value Language
dc.contributor.author Liu, Xiaoshan -
dc.contributor.author Jung, Dawoon -
dc.contributor.author Zhou, Kairu -
dc.contributor.author Lee, Sangwoo -
dc.contributor.author Noh, Kiwan -
dc.contributor.author Khim, Jong Seong -
dc.contributor.author Giesy, John P. -
dc.contributor.author Yim, Un Hyuk -
dc.contributor.author Shim, Won Joon -
dc.contributor.author Choi, Kyungho -
dc.date.accessioned 2020-04-16T09:40:03Z -
dc.date.available 2020-04-16T09:40:03Z -
dc.date.created 2020-01-28 -
dc.date.issued 2018-02 -
dc.identifier.issn 0025-326X -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/1025 -
dc.description.abstract Endocrine disrupting potentials were assessed for sediment samples collected near Hebei Spirit oil spill (HSOS) site, between December 2007 and January 2012. For comparison, major crude oil (CO) of HSOS, or its weathered form were assessed. Both raw extracts (REs) and their fractionated samples were tested using H295R and MVLN/uc bioassays. In H295R cells, REs of crude and weathered oil (WO), and nine of 14 sediments significantly increased E2 levels, which were correlated with the concentrations of PAHs. Steroidogenic disruption potentials of the sediments generally decreased over time. Among silica fractions of all REs, aromatic hydrocarbons (F2) and polar compounds (F3) caused greater E2 levels. While, in MVLN cell bioassay, only three of 14 sediment REs showed estrogen receptor binding potencies, and no temporal trend was observed. In conclusion, oil spill can cause endocrine disruption in the affected ecosystem through steroidogenic alteration for years, and such potencies attenuate over time. -
dc.description.uri 1 -
dc.language English -
dc.publisher PERGAMON-ELSEVIER SCIENCE LTD -
dc.subject EFFECT-DIRECTED ANALYSIS -
dc.subject AHR-ACTIVE PAHS -
dc.subject CRUDE-OIL -
dc.subject MEDIATED RESPONSES -
dc.subject HYDROCARBON -
dc.subject TOXICITY -
dc.subject CELLS -
dc.subject ZEBRAFISH -
dc.subject STEROIDOGENESIS -
dc.subject IDENTIFICATION -
dc.title Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill -
dc.type Article -
dc.citation.endPage 272 -
dc.citation.startPage 264 -
dc.citation.title MARINE POLLUTION BULLETIN -
dc.citation.volume 127 -
dc.contributor.alternativeName 임운혁 -
dc.contributor.alternativeName 심원준 -
dc.identifier.bibliographicCitation MARINE POLLUTION BULLETIN, v.127, pp.264 - 272 -
dc.identifier.doi 10.1016/j.marpolbul.2017.11.055 -
dc.identifier.scopusid 2-s2.0-85040797780 -
dc.identifier.wosid 000427332900030 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus EFFECT-DIRECTED ANALYSIS -
dc.subject.keywordPlus AHR-ACTIVE PAHS -
dc.subject.keywordPlus CRUDE-OIL -
dc.subject.keywordPlus MEDIATED RESPONSES -
dc.subject.keywordPlus HYDROCARBON -
dc.subject.keywordPlus TOXICITY -
dc.subject.keywordPlus CELLS -
dc.subject.keywordPlus ZEBRAFISH -
dc.subject.keywordPlus STEROIDOGENESIS -
dc.subject.keywordPlus IDENTIFICATION -
dc.subject.keywordAuthor Hebei Spirit oil spill -
dc.subject.keywordAuthor H295R -
dc.subject.keywordAuthor MVLN -
dc.subject.keywordAuthor Endocrine disrupting potential -
dc.relation.journalWebOfScienceCategory Environmental Sciences -
dc.relation.journalWebOfScienceCategory Marine & Freshwater Biology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Environmental Sciences & Ecology -
dc.relation.journalResearchArea Marine & Freshwater Biology -
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