Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Liu, Xiaoshan | - |
dc.contributor.author | Jung, Dawoon | - |
dc.contributor.author | Zhou, Kairu | - |
dc.contributor.author | Lee, Sangwoo | - |
dc.contributor.author | Noh, Kiwan | - |
dc.contributor.author | Khim, Jong Seong | - |
dc.contributor.author | Giesy, John P. | - |
dc.contributor.author | Yim, Un Hyuk | - |
dc.contributor.author | Shim, Won Joon | - |
dc.contributor.author | Choi, Kyungho | - |
dc.date.accessioned | 2020-04-16T09:40:03Z | - |
dc.date.available | 2020-04-16T09:40:03Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 0025-326X | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/1025 | - |
dc.description.abstract | Endocrine disrupting potentials were assessed for sediment samples collected near Hebei Spirit oil spill (HSOS) site, between December 2007 and January 2012. For comparison, major crude oil (CO) of HSOS, or its weathered form were assessed. Both raw extracts (REs) and their fractionated samples were tested using H295R and MVLN/uc bioassays. In H295R cells, REs of crude and weathered oil (WO), and nine of 14 sediments significantly increased E2 levels, which were correlated with the concentrations of PAHs. Steroidogenic disruption potentials of the sediments generally decreased over time. Among silica fractions of all REs, aromatic hydrocarbons (F2) and polar compounds (F3) caused greater E2 levels. While, in MVLN cell bioassay, only three of 14 sediment REs showed estrogen receptor binding potencies, and no temporal trend was observed. In conclusion, oil spill can cause endocrine disruption in the affected ecosystem through steroidogenic alteration for years, and such potencies attenuate over time. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | EFFECT-DIRECTED ANALYSIS | - |
dc.subject | AHR-ACTIVE PAHS | - |
dc.subject | CRUDE-OIL | - |
dc.subject | MEDIATED RESPONSES | - |
dc.subject | HYDROCARBON | - |
dc.subject | TOXICITY | - |
dc.subject | CELLS | - |
dc.subject | ZEBRAFISH | - |
dc.subject | STEROIDOGENESIS | - |
dc.subject | IDENTIFICATION | - |
dc.title | Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill | - |
dc.type | Article | - |
dc.citation.endPage | 272 | - |
dc.citation.startPage | 264 | - |
dc.citation.title | MARINE POLLUTION BULLETIN | - |
dc.citation.volume | 127 | - |
dc.contributor.alternativeName | 임운혁 | - |
dc.contributor.alternativeName | 심원준 | - |
dc.identifier.bibliographicCitation | MARINE POLLUTION BULLETIN, v.127, pp.264 - 272 | - |
dc.identifier.doi | 10.1016/j.marpolbul.2017.11.055 | - |
dc.identifier.scopusid | 2-s2.0-85040797780 | - |
dc.identifier.wosid | 000427332900030 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | EFFECT-DIRECTED ANALYSIS | - |
dc.subject.keywordPlus | AHR-ACTIVE PAHS | - |
dc.subject.keywordPlus | CRUDE-OIL | - |
dc.subject.keywordPlus | MEDIATED RESPONSES | - |
dc.subject.keywordPlus | HYDROCARBON | - |
dc.subject.keywordPlus | TOXICITY | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | ZEBRAFISH | - |
dc.subject.keywordPlus | STEROIDOGENESIS | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordAuthor | Hebei Spirit oil spill | - |
dc.subject.keywordAuthor | H295R | - |
dc.subject.keywordAuthor | MVLN | - |
dc.subject.keywordAuthor | Endocrine disrupting potential | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Marine & Freshwater Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Marine & Freshwater Biology | - |