Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill SCIE SCOPUS

Cited 2 time in WEB OF SCIENCE Cited 4 time in Scopus
Title
Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays-Reconnaissance at 5 years after Hebei Spirit oil spill
Author(s)
Liu, Xiaoshan; Jung, Dawoon; Zhou, Kairu; Lee, Sangwoo; Noh, Kiwan; Khim, Jong Seong; Giesy, John P.; Yim, Un Hyuk; Shim, Won Joon; Choi, Kyungho
KIOST Author(s)
Yim, Un Hyuk(임운혁)Shim, Won Joon(심원준)
Publication Year
2018-02
Abstract
Endocrine disrupting potentials were assessed for sediment samples collected near Hebei Spirit oil spill (HSOS) site, between December 2007 and January 2012. For comparison, major crude oil (CO) of HSOS, or its weathered form were assessed. Both raw extracts (REs) and their fractionated samples were tested using H295R and MVLN/uc bioassays. In H295R cells, REs of crude and weathered oil (WO), and nine of 14 sediments significantly increased E2 levels, which were correlated with the concentrations of PAHs. Steroidogenic disruption potentials of the sediments generally decreased over time. Among silica fractions of all REs, aromatic hydrocarbons (F2) and polar compounds (F3) caused greater E2 levels. While, in MVLN cell bioassay, only three of 14 sediment REs showed estrogen receptor binding potencies, and no temporal trend was observed. In conclusion, oil spill can cause endocrine disruption in the affected ecosystem through steroidogenic alteration for years, and such potencies attenuate over time.
ISSN
0025-326X
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/1025
DOI
10.1016/j.marpolbul.2017.11.055
Bibliographic Citation
MARINE POLLUTION BULLETIN, v.127, pp.264 - 272, 2018
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Subject
EFFECT-DIRECTED ANALYSIS; AHR-ACTIVE PAHS; CRUDE-OIL; MEDIATED RESPONSES; HYDROCARBON; TOXICITY; CELLS; ZEBRAFISH; STEROIDOGENESIS; IDENTIFICATION
Keywords
Hebei Spirit oil spill; H295R; MVLN; Endocrine disrupting potential
Type
Article
Language
English
Document Type
Article
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Related Researcher
Research Interests

Microplastic pollution,Persistent Organic Pollutants,Oil Pollution,미세플라스틱 오염,잔류성 유기오염물질,유류오염

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